What is NeuroBlate®

The NeuroBlate laser ablation system enables doctors to destroy brain lesions with precision and confidence.

Learn more about the procedure today.

With NeuroBlate, the surgeon attempts to ablate lesions in the brain. Unlike traditional brain surgery, a procedure with the NeuroBlate System does not require a large opening in the skull. Instead, doctors create a small hole in the skull, about the diameter of a pencil. While the patient is in the MRI machine, the doctor guides a small laser device (probe) through the hole into the lesion. The probe delivers laser light energy that heats and destroys the affected tissue. Because the NeuroBlate System is MRI-guided, the neurosurgeon is able to visualize the specific area of the brain to be ablated. The precise nature of the procedure helps to lessen the likelihood of harm to nearby healthy brain tissue.1,2,3,4

NeuroBlate Procedure

Neuroblate laser ablation simulation showing machine

You will receive anesthesia before the procedure. Your doctor will determine what level of anesthesia is right for you. After the procedure, you will have a stitch or two in the skin where the probe was inserted. You may also have scratches on your head from the device that held your head in position.

Experience shows that patients generally tolerate the procedure well, but each patient is different.

NeuroBlate intraoperative image

NeuroBlate is a minimally invasive surgery, a type requiring only a small opening in the body instead of a large incision as in open surgery.

image of NeuroBlate postoperative opening

Minimally invasive procedures are generally well tolerated, have a short recovery time and patients go home with 1-2 stitches.

Each patient is unique. Your doctors are the best qualified to describe specifically how a procedure may affect your outlook.

NeuroBlate System Patient Brochure


  1. Wilson TA, Karajannis MA, and Harter DH. Glioblastoma multiforme: State of the art and future therapeutics. Surg Neurol Int. 2014 May 8;5:64.
  2. Mohammadi, AM and Schroeder, JL. Laser interstitial thermal therapy in treatment of brain tumors – the NeuroBlate® System. Expert Review of Medical Devices 2014 11:2, 109-119.
  3. Sloan AE, Ahluwalia MS, Valerio-Pascua J, et al. Results of the NeuroBlate® System first-in-humans Phase I clinical trial for recurrent glioblastoma: clinical article. J Neurosurg. 2013 Jun;118(6):1202-19.
  4. Carpentier A, McNichols RJ, Stafford RJ, et al. Laser thermal therapy: real-time MRI-guided and computer- controlled procedures for metastatic brain tumors. Lasers Surg Med. 2011 Dec;43(10):943-50.