NeuroBlate fusion brain image

NeuroBlate Fusion Software allows neurosurgeons to plan, deliver, and monitor MRI-guided robotic laser thermotherapy.

Advanced image co-registration tools

  • Precisely shape ablation margins for assured surgical accuracy
  • Accepts image data processed by other imaging software, delivering surgeons needed information to optimize visibility and accuracy of the intended ablation target

Enhanced visualization of the ablation target

  • Ability to delineate the target ablation area or structures from adjacent structures with interactive, multi-planar volume contouring tools

NeuroBlate Fusion Software Workflow Steps

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1: REGISTRATION
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1: REGISTRATION

Load and fuse (co‑register) DICOM image data

  • DICOM image data is loaded in this task
  • Image data sets are co-registered (fused) together using manual or automatic settings
  • Auto and manual registration are used to match the secondary to the master

May 11, 2018
2: VOLUME
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2: VOLUME

Define anatomical regions of the brain

  • The volume task allows users to define anatomical areas of interest in the brain
  • Volumes are most often used to define treatment regions (e.g., tumors)
  • Can also be used to define “no-go” zones (i.e., a sensitive brain area the user does not want to ablate)

May 11, 2018
3: TRAJECTORY
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3: TRAJECTORY

Describe the entry location and anatomical target for probe insertion in the brain

  • A trajectory is essentially a line in 3D space that connects 2 points – entry point & target point

May 11, 2018
4: ALIGN
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4: ALIGN

Define the radial orientation (direction the laser exits the probe) for SideFire

  • The align task is used to define the starting point (0 degree point) of rotation where the laser exits for SideFire

May 11, 2018
5: INSERT
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5: INSERT

Match the software rendered probe to the actual position of the laser probe in the brain

  • The insert task is used to match the probe location in an MRI scan to where NeuroBlate® Fusion Software considers the probe to be
  • The probe void shows up in an MRI scan as a dark black line in the brain
  • Once the trajectory is confirmed, the probe’s target linear and rotary values can be changed
  • Blue is the target
  • Confirming a new target position causes the real probe to move

May 11, 2018
6: TREAT
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6: TREAT

Thermal monitoring  - Laser actuation

  • Targeted cell damage is represented as contours (outlines) on each slice
  • Contours have 3 damage levels:
    • Yellow: Contained tissue has been exposed to the thermal equivalent of 43°C for 2 minutes duration. Tissue outside the yellow contour lines has a higher probability of receiving no thermal damage
    • Blue: Contained tissue has been exposed to the thermal equivalent of 43°C for 10 minutes duration
    • White: Contained tissue has been exposed to the thermal equivalent of 43°C for 60 minutes duration. Preclinical studies indicated that all tissue within this boundary died in ≤48 hours

May 11, 2018

NeuroBlate Fusion Software™ Brochure