Thermal monitoring – Laser actuation
- Targeted cell damage is represented as contours (outlines) on each slice
- Contours have 3 damage levels:
- Yellow: Contained tissue has been exposed to the thermal equivalent of 43°C for 2 minutes duration. Tissue outside the yellow contour lines has a higher probability of receiving no thermal damage
- Blue: Contained tissue has been exposed to the thermal equivalent of 43°C for 10 minutes duration
- White: Contained tissue has been exposed to the thermal equivalent of 43°C for 60 minutes duration. Preclinical studies indicated that all tissue within this boundary died in ≤48 hours
Match the software rendered probe to the actual position of the laser probe in the brain
- The insert task is used to match the probe location in an MRI scan to where NeuroBlate® Fusion™ Software considers the probe to be
- The probe void shows up in an MRI scan as a dark black line in the brain
- Once the trajectory is confirmed, the probe’s target linear and rotary values can be changed
- Blue is the target
- Confirming a new target position causes the real probe to move
Define the radial orientation (direction the laser exits the probe) for SideFire®
- The align task is used to define the starting point (0 degree point) of rotation where the laser exits for SideFire®
Describe the entry location and anatomical target for probe insertion in the brain
- A trajectory is essentially a line in 3D space that connects 2 points – entry point & target point
Define anatomical regions of the brain
- The volume task allows users to define anatomical areas of interest in the brain
- Volumes are most often used to define treatment regions (e.g., tumors)
- Can also be used to define “no-go” zones (i.e., a sensitive brain area the user does not want to ablate)
Load and fuse (co‑register) DICOM image data
- DICOM image data is loaded in this task
- Image data sets are co-registered (fused) together using manual or automatic settings
- Auto and manual registration are used to match the secondary to the master
- Generally minimally invasive procedures are well tolerated and have a short recovery time.
- You will have 1-2 stitches to close the incision.
- You may also have scratches on your head from the device that helps keep your head in position.
- You will schedule follow-up appointment(s) with your doctor as instructed.
Each patient is unique. Your doctor(s) are the best qualified to describe specifically how a procedure may affect your outlook.